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KMID : 1101420180500020183
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Korean Journal of Clinical Laboratory Science
2018 Volume.50 No. 2 p.183 ~ p.189
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Effects of Omega-3 on Lipid and Liver Function Tests
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Choi Woo-Soon
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Abstract
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Omega-3 unsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are found in fish and fish oil. Recent studies have shown that omega-3 fatty acids are effective in cancer, cardiovascular disease, immune system, cirrhosis, and nervous system disorders. In particular, omega-3 was also reported to help improve hyperlipidemia and liver function tests. On the other hand, there are few cases in Korea. This study examined whether omega-3 is effective in improving hyperlipemia and liver function by taking 1 gm/day for 2 weeks. As a result, AST was decreased in the liver function test, and GGT related to alcoholic hepatitis and fatty liver showed significant results. Omega-3 has been shown to help improve the liver function. The triglyceride, total cholesterol, and low density cholesterol associated with cardiovascular disease decreased after omega-3 ingestion, particularly high density cholesterol. Omega-3 has also been shown to improve the hyperlipidemia. Comparisons between males and females before and after the ingestion of omega-3 showed significant results in AST (P＜0.01) from the male group and in GGT (P＜0.01) and high density cholesterol (P＜0.01) from the female group. As a result, omega-3 intake can help control and improve liver function and hyperlipidemia.
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KEYWORD
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Gamma-glutamyl transferase, High density lipoprotein cholesterol, Omega-3
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